Trexgenics BILE EXTRACT 125 mg 45% CHOLIC ACID Bile Synthesis Support (100 Capsules) (Pack of 1).

Digests Fats

Bile is a complex, vital, and unique fluid produced by the liver to aid in the digestion of fats in the small intestine. The components of bile are actually quite eclectic. It’s yellow-green in color and composed of 95% water in which the following compounds are dissolved, such as [1, 2, 3]:

• Bile acids and salts
• Phospholipids, cholesterol, and steroid hormones
• Pigments and amino acids
• Electrolytes and vitamins
• Antioxidants like melatonin and glutathione
• Antibodies like IgA
• Heavy metals, drugs, and environmental toxins

Bile Salts Help Remove Toxins

Bile salts help the bile remove toxic substances from the body [22].

This includes drugs, environmental pollutants, and heavy metals such as mercury, lead, silver, and cadmium [1].

Scientists are still debating exactly how bile salts are able to do this. Toxins can activate genes that help make bile and phase II detox enzymes. Once the bile is produced, toxins are modified and added to bile along with bile salts. They travel along the gut and can be eliminated through the stool

Bile Salts Help Absorb Fat-Soluble Vitamins

Without bile salts, fat-soluble vitamins (Vitamin A, D, E, and K) cannot be absorbed. Bile salts break down fats and the vitamins dissolved in it into small particles called “micelles”. This allows cells in the gut lining to transport them into the body [15].

And it’s not just that bile salts affect vitamin absorption. Some fat-soluble vitamins themselves can have an effect on the amount of bile the body makes. This way, vitamins regulate their own levels [23].

When the dietary intake of fat-soluble vitamins is high, Vitamin A and vitamin D can deactivate genes that make bile to reduce their own absorption and vice versa. Vitamin A and vitamin D have a strong effect on the receptors that affect bile gene expression (via RAR, RXR, and VDR). This prevents a buildup or deficiency of vitamins A, D, E, and K under normal conditions [23].

In fact, vitamin A may have specific therapeutic potential. It can help the bile re-establish its own feedback loops if it was interrupted for any reason.

Bile Salts Remove Excess Cholesterol

Bile salts are crucial for maintaining balanced cholesterol levels in the body [16].

Producing bile acids from cholesterol is the key pathway for removing cholesterol from the body. About half of the total cholesterol produced in the body is used to make bile acids

Bile Eliminates Bilirubin From the Body

Bile salts play a key role in the removal of bilirubin from the body [18].

Bilirubin is the main pigment in bile. It’s a waste product of hemoglobin breakdown and has harmful effects in the body if accumulated.

Bile Salts Digest Proteins and Starches

Bile salts are essential for digesting proteins and starches. They help break down dietary proteins by enhancing the digestive activity of protease enzymes in the pancreas

Bile Protects the Gut from Infections

Bile protects from gut infections by [1]:

• Making immunoglobulin A (IgA), the first line of defense against harmful microbes
• Stimulating the gut immune system

Help with Diarrhea and Fatty Stool

Disrupted bile flow leads to fat buildup in the gut and stool, which causes diarrhea and stomach pain.